The most common symptoms people with HHS have are heart palpitations and arrhythmia. People usually present with atrial fibrillation; however, other forms of arrythmia may be developed, such as atrial tachycardia, premature ventricular contraction, and atrial flutter. Patients with HHS also frequently report precordial pain, sweating, anxiety, shortness of breath, and syncope. Strokes and cardiac arrest can also occur in people with this syndrome. People with Holiday heart syndrome have a heightened risk of dilated cardiomyopathy, rhabdomyolysis, acute kidney injury, and electrical injuries. The heightened level of acetaldehyde this syndrome causes can result in mitochondrial dysfunction, valvular disease, oxidative damage, cell death, lowered effects of cardioprotective molecules, and an altered calcium transport and protein synthesis system. If left untreated, it can result in thrombosis, pneumonia, cirrhosis, and heart failure. For most patients with HHS the syndrome only lasts 24 hours. However for 26% of people with this syndrome, they reexperience an episode of it within the next year. To treat patients with this condition cardioversion or other treatments for arrhythmia are used.